Another important anti-oxidant, Uric Acid

Another important anti-oxidant, Uric Acid, to the mix and show how vitamin E helps maintain anti-oxidant rather than "gouty levels" of uric acid in blood. 

Uric acid via the p53 gene (tumor suppressor) and GLUT-9 uric acid transporter is theorized to be another powerful intracellular anti-oxidant (1). In fact, high uric acid levels in higher primates/humans may be reason for longer life span (1). Of course, uric acid also related to the development of gout (1). 

By supplementing with vitamin E, one study I found showed that in rats, there was an increase in urinary excretion of uric acid (2). Possibly, the vitamin E allows the cells to maintain level of anti-oxidation which allows reduction in serum uric acid levels? Supplementing with vitamin E may be a consideration then for patients on gout treatment.

1/Itahana Y et al. The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense .Oncogene volume 34, pages 1799–1810 (02 April 2015).

2/Seifi B1, Kadkhodaee M, Zahmatkesh M.. Effect of vitamin E therapy on serum uric acid in DOCA-salt-treated rats.. Acta Physiol Hung. 2011 Jun;98(2):214-20. doi: 10.1556/APhysiol.98.2011.2.13.